Treating chancroid: summary of studies in southern Africa.

Treating chancroid: summary of studies in South Africa.

Recent studies undertaken in southern Africa and elsewhere indicate that many short or single dose treatments are available to treat chancroid. Erythromycin 500 mg three times a day for five days, ciprofloxacin 500 mg, sulphamethopyrazine 800 mg and trimethoprim 1000 mg or sulphametrole 3200 mg and trimethoprim 640 mg as single oral doses, or ceftriaxone 250 mg as a single intramuscular injecti...

Treating chancroid with enoxacin.

Increasing resistance of Haemophilus ducreyi to antimicrobials necessitates further trials of new antimicrobial agents for treating chancroid. Enoxacin has excellent in vitro activity against H ducreyi, and a randomised clinical trial of three doses of enoxacin 400 mg at intervals of 12 hours compared with a single dose of trimethoprim/sulphametrole (TMP/SMT) 640/3200 mg was therefore conducted...

The importance of chancroid in Africa.

THE true incidence of chancroid throughout Africa is unknown, although it is apparent that it is the venereal disease next in importance to syphilis and gonorrhrea, in some places being more prevalent than primary syphilis. Although chancroid is not capable of arresting the development of whole populations, as are gonorrhrea and syphilis by causing sterility and abortion, and although it has no...

Rabies in southern Africa.

The first confirmed outbreak of rabies in Africa, believed to have followed the importation of an infected dog from England in 1892, occurred in the eastern Cape Province of South Africa, and was brought under control in 1894. An unconfirmed epidemic of rabies in dogs occurred in western Zambia in 1901. By the following year the disease had apparently spread along a major trade route, to cause ...

Child Vulnerability and AIDS: Case Studies from Southern Africa